As research continues to unravel the molecular basis of regulatory T cells (Treg), FOXP3 has emerged as a key player in orchestrating development and function of natural Treg. Two recent publications ...
FOXP3 is a master regulator of immune homeostasis expressed specifically in CD4+ CD25+ T regulatory cells controlling their growth, development and function. FOXP3 significance in the normal developm...
Early development and differentiation of nascent T cells that migrate from bone marrow to become mature, naοve T cells, which are capable of responding to antigen takes place inside the thymus. Around...
